Investigation of Zoonotic Bacterial Pathogens Associated with Rodents in Rural Areas of Nellore, India

Rodent species are known to harbour and host various zoonotic pathogens, including bacterial, viral, fungal, protozoal species. Several investigations proved that commensal rats (Rattus spp.) potential transmit drug-resistant hyper-virulent bacterial pathogens humans. India's rapid urbanization developmental activities facilitated live near the human population. However, few information was about associated with rodents their role in risk humans India. The present study aimed (i) investigate presence of (ii) infer prevalence diversity Nellore district, Bacterial determined by isolation identification techniques. isolated cultures were submitted for phenotypic observation, biochemical using VITEK 2 compact automated system, molecular detection DNA extraction amplification 16S rRNA gene. A diversified community belonging 14 detected from all collected animals. species' comparatively higher black (n=66) than brown (n=27). 46 out 93 found be positive (49.4%) presence. significant variation between both rodent highest recorded Bacillus spp. (36%) followed E. coli (29%). Klebsiella pneumoniae as 17%, which 18% 14% rats. Listeria spp.'s 23.6%, but a observed (25.7%). Surprisingly, an uncommon pathogen, Sphingomonas paucimobilis, These results suggest Rattus suspected carriers transmitting